Inferring gene regulatory networks by singular value decomposition and gravitation field algorithm.

Reconstruction of gene regulatory networks (GRNs) is of utmost interest and has become a challenge computational problem in system biology. However, every existing inference algorithm from gene expression profiles has its own advantages and disadvantages. In particular, the effectiveness and efficie...

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Bibliographic Details
Main Authors: Ming Zheng, Jia-nan Wu, Yan-xin Huang, Gui-xia Liu, You Zhou, Chun-guang Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3514269?pdf=render