Nerve Demyelination Increases Metabotropic Glutamate Receptor Subtype 5 Expression in Peripheral Painful Mononeuropathy

Nerve Demyelination Increases Metabotropic Glutamate Receptor Subtype 5 Expression in Peripheral Painful Mononeuropathy

Wallerian degeneration or nerve demyelination, arising from spinal nerve compression, is thought to bring on chronic neuropathic pain. The widely distributed metabotropic glutamate receptor subtype 5 (mGluR5) is involved in modulating nociceptive transmission. The purpose of this study was to invest...

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Bibliographic Details
Main Authors: Miau-Hwa Ko, Yu-Lin Hsieh, Sung-Tsang Hsieh, To-Jung Tseng
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:International Journal of Molecular Sciences
Subjects:
chronic constriction injury
peripheral hypersensitivities
metabotropic glutamate receptor subtype 5 (mGluR5)
2-methyl-6-(phenylethynyl)-pyridine (MPEP)
cutaneous denervation
nerve demyelination
Online Access:http://www.mdpi.com/1422-0067/16/3/4642

Internet

http://www.mdpi.com/1422-0067/16/3/4642

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