Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression.

Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression.

<h4>Background</h4>Gliomas are thought to form by clonal expansion from a single cell-of-origin, and progression-associated mutations to occur in its progeny cells. Glioma progression is associated with elevated growth factor signaling and loss of function of tumor suppressors Ink4a, Arf...

Full description

Bibliographic Details
Main Authors: Elena I Fomchenko, Joseph D Dougherty, Karim Y Helmy, Amanda M Katz, Alexander Pietras, Cameron Brennan, Jason T Huse, Ana Milosevic, Eric C Holland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21754979/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21754979/?tool=EBI

Similar Items