Aberrant DNA Methylation of ABC Transporters in Cancer
ATP-binding cassette (ABC) transporters play a crucial role in multidrug resistance (MDR) of cancers. They function as efflux pumps, resulting in limited effectiveness or even failure of therapy. Increasing evidence suggests that ABC transporters are also involved in tumor initiation, progression, a...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/10/2281 |