Modulatory Effect of Guinep (Melicoccus bijugatus Jacq) Fruit Pulp Extract on Isoproterenol-Induced Myocardial Damage in Rats. Identification of Major Metabolites Using High Resolution UHPLC Q-Orbitrap Mass Spectrometry

Modulatory Effect of Guinep (Melicoccus bijugatus Jacq) Fruit Pulp Extract on Isoproterenol-Induced Myocardial Damage in Rats. Identification of Major Metabolites Using High Resolution UHPLC Q-Orbitrap Mass Spectrometry

Guinep is traditionally used in the management of cardiovascular ailments. This study aims to evaluate its medicinal constituents and effects in the management of myocardial injury in an experimental isoproterenol (ISO) rat model. Sprague-Dawley rats were randomly assigned to four groups: Group 1 wa...

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Bibliographic Details
Main Authors: Chukwuemeka R. Nwokocha, Isheba Warren, Javier Palacios, Mario Simirgiotis, Magdalene Nwokocha, Sharon Harrison, Rory Thompson, Adrian Paredes, Jorge Bórquez, Astrid Lavado, Fredi Cifuentes
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
Melicoccus bijugatus
isoproterenol
myocardial infarction
high-resolution orbitrap mass spectrometry
rat
Online Access:http://www.mdpi.com/1420-3049/24/2/235

Internet

http://www.mdpi.com/1420-3049/24/2/235

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