Clinical significance of combined circulating TERT promoter mutations and miR-122 expression for screening HBV-related hepatocellular carcinoma

Abstract Telomerase reverse-transcriptase (TERT) gene promoter mutations in circulating cell-free DNA (cfDNA) as well as the levels of circulating microRNA-122 (miR-122) have been reported as potential noninvasive biomarkers for several. This study evaluates the diagnostic performance of potent biom...

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Bibliographic Details
Main Authors: Ngo Tat Trung, Nghiem Xuan Hoan, Pham Quang Trung, Mai Thanh Binh, Hoang Van Tong, Nguyen Linh Toan, Mai Hong Bang, Le Huu Song
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-65213-8