No evidence of involvement of E-cadherin in cell fate specification or the segregation of Epi and PrE in mouse blastocysts.

During preimplantation mouse development stages, emerging pluripotent epiblast (Epi) and extraembryonic primitive endoderm (PrE) cells are first distributed in the blastocyst in a "salt-and-pepper" manner before they segregate into separate layers. As a result of segregation, PrE cells bec...

Full description

Bibliographic Details
Main Authors: Katarzyna Filimonow, Nestor Saiz, Aneta Suwińska, Tomasz Wyszomirski, Joanna B Grabarek, Elisabetta Ferretti, Anna Piliszek, Berenika Plusa, Marek Maleszewski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212109