Transcriptional profiling of liver in riboflavin-deficient chicken embryos explains impaired lipid utilization, energy depletion, massive hemorrhaging, and delayed feathering

Transcriptional profiling of liver in riboflavin-deficient chicken embryos explains impaired lipid utilization, energy depletion, massive hemorrhaging, and delayed feathering

Abstract Background A strain of Leghorn chickens (rd/rd), unable to produce a functional riboflavin-binding protein, lays riboflavin-deficient eggs, in which all embryos suddenly die at mid-incubation (days 13-15). This malady, caused by riboflavin deficiency, leads to excessive lipid accumulation i...

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Bibliographic Details
Main Authors: Larry A. Cogburn, Danielle N. Smarsh, Xiaofei Wang, Nares Trakooljul, Wilfrid Carré, Harold B. White
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Genomics
Subjects:
Microarray analysis
Riboflavin deficiency
Expression profiling
Impaired lipid metabolism
β-oxidation
Protein catabolism
Online Access:http://link.springer.com/article/10.1186/s12864-018-4568-2

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http://link.springer.com/article/10.1186/s12864-018-4568-2

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