SH3KBP1 Promotes Glioblastoma Tumorigenesis by Activating EGFR Signaling

Glioblastoma (GBM) is the most common and aggressive brain tumor in adults. Overexpression or activation of epidermal growth factor receptor (EGFR) occurs commonly in multiple human cancers and promotes tumorigenesis. However, the underlying molecular mechanism of EGFR aberrant activation and the do...

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Bibliographic Details
Main Authors: Hai Song, Yanpei Wang, Chaojia Shi, Jianxiang Lu, Tian Yuan, Xiangpeng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.583984/full