0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial

0.9% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU—a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial

Abstract Background Intravenous fluid therapy represents the most common intervention critically ill patients are exposed to. Hyperchloremia and metabolic acidosis associated with 0.9% sodium chloride have been observed to lead to worse outcomes, including mortality. Balanced solutions, such as Plas...

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Bibliographic Details
Main Authors: Sainath Raman, Andreas Schibler, Renate Le Marsney, Peter Trnka, Melanie Kennedy, Adrian Mattke, Kristen Gibbons, Luregn J. Schlapbach
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Trials
Subjects:
Balanced solutions
Bolus
Child
Critical care
Intravenous fluid therapy
Online Access:https://doi.org/10.1186/s13063-021-05376-5

Internet

https://doi.org/10.1186/s13063-021-05376-5

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