Evolution of JAK-STAT pathway components: mechanisms and role in immune system development.

<h4>Background</h4>Lying downstream of a myriad of cytokine receptors, the Janus kinase (JAK)-Signal transducer and activator of transcription (STAT) pathway is pivotal for the development and function of the immune system, with additional important roles in other biological systems. To...

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Bibliographic Details
Main Authors: Clifford Liongue, Lynda A O'Sullivan, Monique C Trengove, Alister C Ward
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22412924/?tool=EBI