Large-scale analysis of B-cell epitopes of envelope: Implications for Zika vaccine and immunotherapeutic development [version 2; peer review: 2 approved]

Background: Cases of the re-emergence of Zika virus in 2015 were associated with severe neurologic complications, including Gillien-Barre syndrome in adults and congenital Zika syndrome in newborns. The major structural determinant of immunity to the Zika virus is the E protein. Although B-cell epit...

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Bibliographic Details
Main Authors: Iman Almansour, Rahaf Alfares, Halah Aljofi
Format: Article
Language:English
Published: F1000 Research Ltd 2019-06-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-1624/v2