Lipase Catalysed Kinetic Resolution of Racemic 1,2-Diols Containing a Chiral Quaternary Center
Optically active 1,2-diols are valuable buildings blocks in organic synthesis. In the present paper, a set of racemic 1,2-diols with an ester functional group are prepared, starting from α-ketoesters in a three-step procedure with moderate yields. The racemic 1,2-diols, containing a chiral...
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Format: | Article |
Language: | English |
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MDPI AG
2018-06-01
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Series: | Molecules |
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Online Access: | http://www.mdpi.com/1420-3049/23/7/1585 |