Oridonin inhibits tumor growth and metastasis through anti-angiogenesis by blocking the Notch signaling.

While significant progress has been made in understanding the anti-inflammatory and anti-proliferative effects of the natural diterpenoid component Oridonin on tumor cells, little is known about its effect on tumor angiogenesis or metastasis and on the underlying molecular mechanisms. In this study,...

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Bibliographic Details
Main Authors: Yanmin Dong, Tao Zhang, Jingjie Li, Huayun Deng, Yajuan Song, Dong Zhai, Yi Peng, Xiaoling Lu, Mingyao Liu, Yongxiang Zhao, Zhengfang Yi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4259472?pdf=render