miR-190 suppresses breast cancer metastasis by regulation of TGF-β-induced epithelial–mesenchymal transition

miR-190 suppresses breast cancer metastasis by regulation of TGF-β-induced epithelial–mesenchymal transition

Abstract Background Breast cancer is the most common cancer among women worldwide and metastasis is the leading cause of death among patients with breast cancer. The transforming growth factor-β (TGF-β) pathway plays critical roles during breast cancer epithelial–mesenchymal transition (EMT) and met...

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Bibliographic Details
Main Authors: Yue Yu, Wei Luo, Zheng-Jun Yang, Jiang-Rui Chi, Yun-Rui Li, Yu Ding, Jie Ge, Xin Wang, Xu-Chen Cao
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Molecular Cancer
Subjects:
Breast cancer
Transforming growth factor-β
Epithelial to mesenchymal transition
miR-190
SMAD2
ZEB1
Online Access:http://link.springer.com/article/10.1186/s12943-018-0818-9

Internet

http://link.springer.com/article/10.1186/s12943-018-0818-9

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