Effects of an alpha-4 integrin inhibitor on restenosis in a new porcine model combining endothelial denudation and stent placement.

Restenosis remains the main complication of balloon angioplasty and/or stent implantation. Preclinical testing of new pharmacologic agents preventing restenosis largely rely on porcine models, where restenosis is assessed after endothelial abrasion of the arterial wall or stent implantation. We comb...

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Bibliographic Details
Main Authors: Anne Braun, Lilibeth Dofiles, Serge Rousselle, Luis Guerrero, Jane Gunther, Ted Yednock, Alain Stricker-Krongrad, Elizabeth Messersmith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3001476?pdf=render