Discovering the Mutational Profile of Early Colorectal Lesions: A Translational Impact

Discovering the Mutational Profile of Early Colorectal Lesions: A Translational Impact

Colorectal cancer (CRC) develops through a multi-step process characterized by the acquisition of multiple somatic mutations in oncogenes and tumor-suppressor genes, epigenetic alterations and genomic instability. These events lead to the progression from precancerous lesions to advanced carcinomas....

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Bibliographic Details
Main Authors: Chiara Alquati, Anna Prossomariti, Giulia Piazzi, Francesco Buttitta, Franco Bazzoli, Luigi Laghi, Luigi Ricciardiello
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
colorectal cancer
familial adenomatous polyposis
lynch syndrome
conventional colorectal adenomas
serrated colorectal adenomas
Online Access:https://www.mdpi.com/2072-6694/13/9/2081

Internet

https://www.mdpi.com/2072-6694/13/9/2081

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