Generation of human erythroblast-derived iPSC line using episomal reprogramming system

Peripheral blood mononuclear cells were isolated and cultured to a pure pro-EBL population and reprogrammed using episomal plasmids. The pluripotency of transgene-free induced pluripotent stem cell (iPSC) line was verified by the expression of pluripotency-associated markers and by in vitro spontane...

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Bibliographic Details
Main Authors: Eszter Varga, Marten Hansen, Tatjana Wüst, Marieke von Lindern, Emile van den Akker
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117302064