Hemozoin-catalyzed precipitation polymerization as an assay for malaria diagnosis

Methods to diagnose malaria are of interest but can be costly or not sensitive enough to detect low levels of parasitemia. Here the authors report an ultrasensitive method by using hemozoin (a biomarker of all Plasmodium species) to catalyse the polymerization of N-isopropylacrylamide.

Bibliographic Details
Main Authors: Omar Rifaie-Graham, Jonas Pollard, Samuel Raccio, Sandor Balog, Sebastian Rusch, María Andrea Hernández-Castañeda, Pierre-Yves Mantel, Hans-Peter Beck, Nico Bruns
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09122-z