Exploring the Roles of HERC2 and the NEDD4L HECT E3 Ubiquitin Ligase Subfamily in p53 Signaling and the DNA Damage Response

Cellular homeostasis is governed by the precise expression of genes that control the translation, localization, and termination of proteins. Oftentimes, environmental and biological factors can introduce mutations into the genetic framework of cells during their growth and division, and these geneti...

Full description

Bibliographic Details
Main Authors: Nicholas A. Mathieu, Rafael H. Levin, Donald E. Spratt
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
p53
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.659049/full