Positive Feedback Loop of Autocrine BDNF from Microglia Causes Prolonged Microglia Activation

Background/Aims: Microglia, which represent the immune cells of the central nervous system (CNS), have long been a subject of study in CNS disease research. Substantial evidence indicates that microglial activation functions as a strong neuro-inflammatory response in neuropathic pain, promoting the...

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Bibliographic Details
Main Authors: Xin Zhang, Lulu Zeng, Tingting Yu, Yongming Xu, Shaofeng Pu, Dongping Du, Wei Jiang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
ATP
Online Access:http://www.karger.com/Article/FullText/363036