Prophylactic antenatal N-Acetyl Cysteine administration combined with postnatal administration can decrease mortality and injury markers associated with necrotizing enterocolitis in a rat model.

Prophylactic antenatal N-Acetyl Cysteine administration combined with postnatal administration can decrease mortality and injury markers associated with necrotizing enterocolitis in a rat model.

BACKGROUND:Necrotizing enterocolitis (NEC) is a devastating gastrointestinal disease of neonates, especially premature neonates. To date, there is no prophylactic treatment against NEC, except breast milk and slow increase in enteral feeding, and there is no antenatal prophylaxis. AIMS:To assess pos...

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Bibliographic Details
Main Authors: Osnat Zmora, Ola Gutzeit, Linoy Segal, Sari Boulos, Zvika Millo, Yuval Ginsberg, Nizar Khatib, Fadwa Dabbah-Assad, Ofer Fainaru, Zeev Weiner, Ron Beloosesky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233612

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https://doi.org/10.1371/journal.pone.0233612

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