Exosome miR-371b-5p promotes proliferation of lung alveolar progenitor type II cells by using PTEN to orchestrate the PI3K/Akt signaling

Exosome miR-371b-5p promotes proliferation of lung alveolar progenitor type II cells by using PTEN to orchestrate the PI3K/Akt signaling

Abstract Background Pathways directing endogenous stem/progenitor cells to restore normal architecture and function of damaged/diseased lungs remain underexplored. Published data have revealed that alveolar progenitor type II cell (ATIIC)-derived signaling promotes re-epithelialization of injured al...

Full description

Bibliographic Details
Main Authors: Yuan Quan, Zhaohua Wang, Ling Gong, Xinmiao Peng, Melissa A. Richard, Junlan Zhang, Myriam Fornage, Joseph L. Alcorn, Dachun Wang
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Stem Cell Research & Therapy
Subjects:
Exosome miRNAs
MiR-371b-5p
PTEN/PI3K/Akt signaling
Lung alveolar progenitor type II cells
Lung injury
Online Access:http://link.springer.com/article/10.1186/s13287-017-0586-2

Internet

http://link.springer.com/article/10.1186/s13287-017-0586-2

Similar Items