Adenine-Induced Chronic Renal Failure in Rats: A Model of Chronic Renocardiac Syndrome with Left Ventricular Diastolic Dysfunction but Preserved Ejection Fraction

Adenine-Induced Chronic Renal Failure in Rats: A Model of Chronic Renocardiac Syndrome with Left Ventricular Diastolic Dysfunction but Preserved Ejection Fraction

Background/Aims: Cardiovascular disease is the major cause of death in patients with chronic kidney disease (CKD). Rats with adenine-induced chronic renal failure (ACRF) develop severe renal insufficiency and metabolic abnormalities that closely resemble those in patients with uremia. The aim of the...

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Bibliographic Details
Main Authors: Pavlos Kashioulis, Jaana Lundgren, Emman Shubbar, Lisa Nguy, Aso Saeed, Cecilia Wallentin Guron, Gregor Guron
Format: Article
Language:English
Published: Karger Publishers 2018-07-01
Series:Kidney & Blood Pressure Research
Subjects:
Chronic kidney disease
Adenine
Hypertension
Left ventricular hypertrophy
Diastolic dysfunction
Online Access:https://www.karger.com/Article/FullText/491056

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https://www.karger.com/Article/FullText/491056

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