Inhibition of proliferation, migration and proteolysis contribute to corticosterone-mediated inhibition of angiogenesis.

Inhibition of proliferation, migration and proteolysis contribute to corticosterone-mediated inhibition of angiogenesis.

The angiostatic nature of pharmacological doses of glucocorticoid steroids is well known. However, the consequences of pathophysiological elevation of endogenous glucocorticoids are not well established. In the current study, we hypothesized that the angiostatic effect of corticosterone, an endogeno...

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Main Authors: Eric A Shikatani, Anastassia Trifonova, Erin R Mandel, Sammy T K Liu, Emilie Roudier, Anna Krylova, Andrei Szigiato, Jacqueline Beaudry, Michael C Riddell, Tara L Haas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3462789?pdf=render

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http://europepmc.org/articles/PMC3462789?pdf=render

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