Breaking Bottlenecks for the TCR Therapy of Cancer

Immune checkpoint inhibitors have redefined the treatment of cancer, but their efficacy depends critically on the presence of sufficient tumor-specific lymphocytes, and cellular immunotherapies develop rapidly to fill this gap. The paucity of suitable extracellular and tumor-associated antigens in s...

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Bibliographic Details
Main Authors: Lena Gaissmaier, Mariam Elshiaty, Petros Christopoulos
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/9/2095