Chikungunya virus entry is strongly inhibited by phospholipase A2 isolated from the venom of Crotalus durissus terrificus

Chikungunya virus entry is strongly inhibited by phospholipase A2 isolated from the venom of Crotalus durissus terrificus

Abstract Chikungunya virus (CHIKV) is the etiologic agent of Chikungunya fever, a globally spreading mosquito-borne disease. There is no approved antiviral or vaccine against CHIKV, highlighting an urgent need for novel therapies. In this context, snake venom proteins have demonstrated antiviral act...

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Bibliographic Details
Main Authors: Igor Andrade Santos, Jacqueline Farinha Shimizu, Débora Moraes de Oliveira, Daniel Oliveira Silva Martins, Léia Cardoso-Sousa, Adélia Cristina Oliveira Cintra, Victor Hugo Aquino, Suely Vilela Sampaio, Nilson Nicolau-Junior, Robinson Sabino-Silva, Andres Merits, Mark Harris, Ana Carolina Gomes Jardim
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88039-4

Internet

https://doi.org/10.1038/s41598-021-88039-4

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