Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development

Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development

The origins and functions of kidney macrophages in the adult have been explored, but their roles during development remain largely unknown. Here we characterise macrophage arrival, localisation, heterogeneity, and functions during kidney organogenesis. Using genetic approaches to ablate macrophages,...

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Bibliographic Details
Main Authors: David AD Munro, Yishay Wineberg, Julia Tarnick, Chris S Vink, Zhuan Li, Clare Pridans, Elaine Dzierzak, Tomer Kalisky, Peter Hohenstein, Jamie A Davies
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-02-01
Series:eLife
Subjects:
phagocytosis
nephron
blood vessel
morphogenesis
cell migration
Online Access:https://elifesciences.org/articles/43271

Internet

https://elifesciences.org/articles/43271

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