Sequence-only evolutionary and predicted structural features for the prediction of stability changes in protein mutants

Sequence-only evolutionary and predicted structural features for the prediction of stability changes in protein mutants

<p>Abstract</p> <p>Background</p> <p>Even a single amino acid substitution in a protein sequence may result in significant changes in protein stability, structure, and therefore in protein function as well. In the post-genomic era, computational methods for predicting s...

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Bibliographic Details
Main Authors:	Folkman Lukas, Stantic Bela, Sattar Abdul
Format:	Article
Language:	English
Published:	BMC 2013-01-01
Series:	BMC Bioinformatics

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