Sequence-only evolutionary and predicted structural features for the prediction of stability changes in protein mutants
<p>Abstract</p> <p>Background</p> <p>Even a single amino acid substitution in a protein sequence may result in significant changes in protein stability, structure, and therefore in protein function as well. In the post-genomic era, computational methods for predicting s...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2013-01-01
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Series: | BMC Bioinformatics |