Age is not just a number: Naive T cells increase their ability to persist in the circulation over time.
The processes regulating peripheral naive T-cell numbers and clonal diversity remain poorly understood. Conceptually, homeostatic mechanisms must fall into the broad categories of neutral (simple random birth-death models), competition (regulation of cell numbers through quorum-sensing, perhaps via...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-04-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC5894957?pdf=render |