Age is not just a number: Naive T cells increase their ability to persist in the circulation over time.

The processes regulating peripheral naive T-cell numbers and clonal diversity remain poorly understood. Conceptually, homeostatic mechanisms must fall into the broad categories of neutral (simple random birth-death models), competition (regulation of cell numbers through quorum-sensing, perhaps via...

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Bibliographic Details
Main Authors: Sanket Rane, Thea Hogan, Benedict Seddon, Andrew J Yates
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC5894957?pdf=render