Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It.

Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It.

TNF-α stimulated gene/protein 6 (TNFAIP6/TSG-6) is a multifunctional protein that has a number of potential therapeutic applications. Experiments and clinical trials with TSG-6, however, have been limited by the technical difficulties of producing the recombinant protein. We prepared stable clones o...

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Bibliographic Details
Main Authors: Dong-Ki Kim, Hosoon Choi, Hidetaka Nishida, Joo Youn Oh, Carl Gregory, Ryang Hwa Lee, Ji Min Yu, Jun Watanabe, Su Yeon An, Thomas J Bartosh, Darwin J Prockop
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4721919?pdf=render

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http://europepmc.org/articles/PMC4721919?pdf=render

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