Critical role for adenosine receptor A2a in β-cell proliferation

Objective: Pharmacological activation of adenosine signaling has been shown to increase β-cell proliferation and thereby β-cell regeneration in zebrafish and rodent models of diabetes. However, whether adenosine has an endogenous role in regulating β-cell proliferation is unknown. The objective of t...

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Bibliographic Details
Main Authors: Nadja Schulz, Ka-Cheuk Liu, Jérémie Charbord, Charlotte L. Mattsson, Lingjie Tao, Dominika Tworus, Olov Andersson
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816301570