Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability

Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability

Cancer cell metabolism is heavily influenced by microenvironmental factors, including nutrient availability. Therefore, knowledge of microenvironmental nutrient levels is essential to understand tumor metabolism. To measure the extracellular nutrient levels available to tumors, we utilized quantitat...

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Bibliographic Details
Main Authors: Mark R Sullivan, Laura V Danai, Caroline A Lewis, Sze Ham Chan, Dan Y Gui, Tenzin Kunchok, Emily A Dennstedt, Matthew G Vander Heiden, Alexander Muir
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-04-01
Series:eLife
Subjects:
cancer
metabolism
microenvironment
mass spectrometry
metabolomics
pancreatic adenocarcinoma
Online Access:https://elifesciences.org/articles/44235

Internet

https://elifesciences.org/articles/44235

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