Synthesis of Thiophene and NO-Curcuminoids for Antiinflammatory and Anti-Cancer Activities
In search of better NSAIDs four novel nitric oxide donating derivatives of curcumin (compounds 9a–d), and four thiophene curcuminoids (compounds 10a–c, 11) have been synthesised. The cytotoxic effects of these compounds along with the lead compound curcumin (7) and their effect on the production of...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2013-01-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/18/2/1483 |