Genotype-specific acquisition, evolution and adaptation of characteristic mutations in hepatitis E virus

Hepatitis E virus (HEV) infection is a major cause of acute hepatitis but also provokes chronic infection in immunocompromised patients. Although the pathogenesis and treatment outcome involve complex interplay between the virus and host, the nature of adaptive responses of HEV to the host immune sy...

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Bibliographic Details
Main Authors: Aqsa Ikram, Mohamad S. Hakim, Jian-hua Zhou, Wenshi Wang, Maikel P. Peppelenbosch, Qiuwei Pan
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Virulence
Subjects:
Online Access:http://dx.doi.org/10.1080/21505594.2017.1358349