Identification of High-Risk Plaques by MRI and Fluorescence Imaging in a Rabbit Model of Atherothrombosis.

INTRODUCTION:The detection of atherosclerotic plaques at risk for disruption will be greatly enhanced by molecular probes that target vessel wall biomarkers. Here, we test if fluorescently-labeled Activatable Cell Penetrating Peptides (ACPPs) could differentiate stable plaques from vulnerable plaque...

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Bibliographic Details
Main Authors: Ning Hua, Fred Baik, Tuan Pham, Alkystis Phinikaridou, Nick Giordano, Beth Friedman, Michael Whitney, Quyen T Nguyen, Roger Y Tsien, James A Hamilton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4598148?pdf=render