Synthesis and Application of an Aldazine-Based Fluorescence Chemosensor for the Sequential Detection of Cu2+ and Biological Thiols in Aqueous Solution and Living Cells

A fluorescence chemosensor, 2-hydroxy-1-naphthaldehyde azine (HNA) was designed and synthesized for sequential detection of Cu2+ and biothiols. It was found that HNA can specifically bind to Cu2+ with 1:1 stoichiometry, accompanied with a dramatic fluorescence quenching and a remarkable bathochromic...

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Bibliographic Details
Main Authors: Hongmin Jia, Ming Yang, Qingtao Meng, Guangjie He, Yue Wang, Zhizhi Hu, Run Zhang, Zhiqiang Zhang
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/16/1/79