Empirical evaluation of oligonucleotide probe selection for DNA microarrays.

DNA-based microarrays are increasingly central to biomedical research. Selecting oligonucleotide sequences that will behave consistently across experiments is essential to the design, production and performance of DNA microarrays. Here our aim was to improve on probe design parameters by empirically...

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Bibliographic Details
Main Authors: Jennifer G Mulle, Viren C Patel, Stephen T Warren, Madhuri R Hegde, David J Cutler, Michael E Zwick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2847945?pdf=render