Revisiting genetic artifacts on DNA methylation microarrays exposes novel biological implications

Abstract Background Illumina DNA methylation microarrays enable epigenome-wide analysis vastly used for the discovery of novel DNA methylation variation in health and disease. However, the microarrays’ probe design cannot fully consider the vast human genetic diversity, leading to genetic artifacts....

Full description

Bibliographic Details
Main Authors: Benjamin Planterose Jiménez, Manfred Kayser, Athina Vidaki
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02484-y