Revisiting genetic artifacts on DNA methylation microarrays exposes novel biological implications
Abstract Background Illumina DNA methylation microarrays enable epigenome-wide analysis vastly used for the discovery of novel DNA methylation variation in health and disease. However, the microarrays’ probe design cannot fully consider the vast human genetic diversity, leading to genetic artifacts....
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-09-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-021-02484-y |