Low Replicative Stress Triggers Cell-Type Specific Inheritable Advanced Replication Timing

Low Replicative Stress Triggers Cell-Type Specific Inheritable Advanced Replication Timing

DNA replication timing (RT), reflecting the temporal order of origin activation, is known as a robust and conserved cell-type specific process. Upon low replication stress, the slowing of replication forks induces well-documented RT delays associated to genetic instability, but it can also generate...

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Bibliographic Details
Main Authors: Lilas Courtot, Elodie Bournique, Chrystelle Maric, Laure Guitton-Sert, Miguel Madrid-Mencía, Vera Pancaldi, Jean-Charles Cadoret, Jean-Sébastien Hoffmann, Valérie Bergoglio
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
DNA replication stress
DNA replication timing
chromatin accessibility
DNA damage
Online Access:https://www.mdpi.com/1422-0067/22/9/4959

Internet

https://www.mdpi.com/1422-0067/22/9/4959

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