Modeling Maintenance of Long-Term Potentiation in Clustered Synapses: Long-Term Memory without Bistability
Memories are stored, at least partly, as patterns of strong synapses. Given molecular turnover, how can synapses maintain strong for the years that memories can persist? Some models postulate that biochemical bistability maintains strong synapses. However, bistability should give a bimodal distribut...
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2015-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2015/185410 |