The elastin peptide VGVAPG increases CD4+ T-cell IL-4 production in patients with chronic obstructive pulmonary disease

The elastin peptide VGVAPG increases CD4+ T-cell IL-4 production in patients with chronic obstructive pulmonary disease

Abstract Background In chronic obstructive pulmonary disease (COPD), lung-infiltrating inflammatory cells secrete proteases and participate in elastin breakdown and genesis of elastin-derived peptides (EP). In the present study, we hypothesized that the pattern of T lymphocytes cytokine expression m...

Full description

Bibliographic Details
Main Authors: Flora Lemaire, Sandra Audonnet, Jeanne-Marie Perotin, Pierre Gaudry, Sandra Dury, Julien Ancel, François Lebargy, Frank Antonicelli, Gaëtan Deslée, Richard Le Naour
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Respiratory Research
Subjects:
COPD
T cells
Elastin peptides
Cytokines
IL-4
Flow cytometry
Online Access:https://doi.org/10.1186/s12931-020-01609-4

Internet

https://doi.org/10.1186/s12931-020-01609-4

Similar Items