ATRX Alteration Contributes to Tumor Growth and Immune Escape in Pleomorphic Sarcomas

ATRX Alteration Contributes to Tumor Growth and Immune Escape in Pleomorphic Sarcomas

Whole genome and transcriptome sequencing of a cohort of 67 leiomyosarcomas has been revealed <i>ATRX</i> to be one of the most frequently mutated genes in leiomyosarcomas after <i>TP53</i> and <i>RB1</i>. While its function is well described in the alternative le...

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Bibliographic Details
Main Authors: Lucie Darmusey, Gaëlle Pérot, Noémie Thébault, Sophie Le Guellec, Nelly Desplat, Laëtitia Gaston, Lucile Delespaul, Tom Lesluyes, Elodie Darbo, Anne Gomez-Brouchet, Elodie Richard, Jessica Baud, Laura Leroy, Jean-Michel Coindre, Jean-Yves Blay, Frédéric Chibon
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
sarcomas
ATRX
oncogenesis
mast cells
alteration
Online Access:https://www.mdpi.com/2072-6694/13/9/2151

Internet

https://www.mdpi.com/2072-6694/13/9/2151

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