CYP4F3B is induced by PGA1 in human liver cells: a regulation of the 20-HETE synthesis

The regulation of the human liver-specific cytochrome P450 4F3B (CYP4F3B) isoform, a splice variant of the CYP4F3 gene with strong substrate specificity for long chain fatty acids, is yet an unsolved question. This report provides the first evidence that CYP4F3B is uniquely induced by prostaglandin...

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Bibliographic Details
Main Authors: Joseph Antoun, Sophie Goulitquer, Yolande Amet, Yvonne Dreano, Jean-Pierre Salaun, Laurent Corcos, Emmanuelle Plée-Gautier
Format: Article
Language:English
Published: Elsevier 2008-10-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520346368