Effects of serum albumin on SPR-measured affinity of small molecule inhibitors binding to nerve growth factor
The study of the interactions between a drug and plasma serum proteins are necessary in determining pharmacological and toxicological properties for therapeutic development. Small molecule nerve growth factor (NGF) inhibitors have been investigated for their abilities to inhibit NGF binding to TrkA...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-09-01
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| Series: | Sensing and Bio-Sensing Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221418041730048X |