9. HMG-COA REDUCTASE INHIBITOR IMPROVES ENDOTHELIAL DYSFUNCTION IN SPONTANEOUS HYPERTENSIVE RATS VIA DOWN-REGULATION OF CAVEOLIN-1 AND ACTIVATION OF ENOS

Hypertension is associated with endothelial dysfunction and increased cardiovascular risk. Caveolin-1 regulates nitric oxide(NO) signaling by modulating endothelial nitric oxide synthase(eNOS). The purpose of this study was to examine whether HMG-CoA reductase inhibitor improves impaired endothelial...

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Bibliographic Details
Main Authors: Dong-Ju Choi, Eun-Ji Kim, Min-Jung Park, Jung-Won Suh, Hyuk-Jae Chang, Young-Seok Cho, Tae-Jin Yeon, In-Ho Chae, Kwang-Il Kim, Cheol-Ho Kim, Hyo-soo Kim, Buyng-Hee Oh, Young-Bae Park
Format: Article
Language:English
Published: Atlantis Press 2009-10-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125925782/view