Enhancing sensitivity of pH-weighted MRI with combination of amide and guanidyl CEST

Amide-proton-transfer weighted (APTw) MRI has emerged as a non-invasive pH-weighted imaging technique for studies of several diseases such as ischemic stroke. However, its pH-sensitivity is relatively low, limiting its capability to detect small pH changes. In this work, computer simulations, protam...

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Bibliographic Details
Main Authors: Tao Jin, Ping Wang, T. Kevin Hitchens, Seong-Gi Kim
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:NeuroImage
Subjects:
pH
APT
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811917304767