Histology, immunohistochemistry, and in situ hybridization reveal overlooked Ebola virus target tissues in the Ebola virus disease guinea pig model

Abstract Survivors of Ebola virus infection may become subclinically infected, but whether animal models recapitulate this complication is unclear. Using histology in combination with immunohistochemistry and in situ hybridization in a retrospective review of a guinea pig confirmation-of-virulence s...

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Bibliographic Details
Main Authors: Timothy K. Cooper, Louis Huzella, Joshua C. Johnson, Oscar Rojas, Sri Yellayi, Mei G. Sun, Sina Bavari, Amanda Bonilla, Randy Hart, Peter B. Jahrling, Jens H. Kuhn, Xiankun Zeng
Format: Article
Language:English
Published: Nature Publishing Group 2018-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-19638-x