Populene D Analogues: Design, Concise Synthesis and Antiproliferative Activity

An efficient and concise synthesis of nine populene D analogues was performed using an iodine-catalyzed Prins cyclization as the key transformation. The antiproliferative activity of these new pyrans against several cancer cell lines was then investigated. Among them, an isochromene with moderate ac...

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Bibliographic Details
Main Authors: Kachi R. Kishore Kumar Reddy, Giovanna B. Longato, João E. de Carvalho, Ana L. T. G. Ruiz, Luiz F. Silva, Jr.
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/17/8/9621